Proheparin-binding EGF-like growth factor

BE0018589ProteinHumansHBEGF

Growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. It is acted on by 1 drug in DrugBank.

Gene name
HBEGF
UniProtKB entry
Q99075Swiss-Prot
Cellular location
Secreted, extracellular space
Residues / weight
208 residues · 23,067 Da
Also known as
DTR · DTS · HEGFL

Resolves to

Protein
UniProtQ99075UniProt nameHBEGF_HUMAN
Gene
HGNCHGNC:3059NCBI Gene1839GeneCardsHBEGF
Pharmacology
KEGGhsa:1839
Structure
PDB1XDTPDB2M8S
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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25GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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1+ReferenceStructured and connected to the statements they support
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Which compounds in development act on Proheparin-binding EGF-like growth factor, and which indications are they being tested in?

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