Sortilin

BE0018732ProteinHumansSORT1

Functions as a sorting receptor in the Golgi compartment and as a clearance receptor on the cell surface. It is acted on by 1 drug in DrugBank.

Gene name
SORT1
UniProtKB entry
Q99523Swiss-Prot
Cellular location
Golgi apparatus, Golgi stack membrane
Residues / weight
831 residues · 92,067 Da
Also known as
100 kDa NT receptor · Glycoprotein 95 · Gp95 · Neurotensin receptor 3 · NT3

Resolves to

Protein
UniProtQ99523UniProt nameSORT_HUMAN
Gene
HGNCHGNC:11186NCBI Gene6272GeneCardsSORT1
Pharmacology
IUPHAR/GtoPdb3300KEGGhsa:6272
Structure
PDB3F6KPDB3G2UPDB3G2V
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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1+ReferenceStructured and connected to the statements they support
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Which compounds in development act on Sortilin, and which indications are they being tested in?

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