Oncostatin-M-specific receptor subunit beta

BE0018846ProteinHumansOSMR

Functions as a shared membrane-bound signal-transducing subunit in two distinct receptor complexes, the type II OSM receptor (heterodimer composed of OSMR and IL6ST) and the IL31 receptor complex (heterodimer composed of OSMR and IL31RA) which... It is acted on by 1 drug in DrugBank.

Gene name
OSMR
UniProtKB entry
Q99650Swiss-Prot
Cellular location
Membrane
Residues / weight
979 residues · 110,508 Da
Also known as
IL-31 receptor subunit beta · IL-31R subunit beta · IL-31R-beta · IL-31RB · Interleukin-31 receptor subunit beta

Resolves to

Protein
UniProtQ99650UniProt nameOSMR_HUMAN
Gene
HGNCHGNC:8507NCBI Gene9180GeneCardsOSMR
Pharmacology
KEGGhsa:9180
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
Sign in
15GO termsFunction, process and component, as structured annotations
Sign in
4Pfam domainsDomain architecture mapped to Pfam families and clans
Sign in
3+ReferencesStructured and connected to the statements they support
Sign in

Which compounds in development act on Oncostatin-M-specific receptor subunit beta, and which indications are they being tested in?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In