Galactosylceramide sulfotransferase

BE0018854ProteinHumansGAL3ST1

Catalyzes the transfer of a sulfate group to position 3 of non-reducing beta-galactosyl residues in glycerolipids and sphingolipids, therefore participates in the biosynthesis of sulfoglycolipids (PubMed:8830034, PubMed:9030544). It is acted on by 1 drug in DrugBank.

Gene name
GAL3ST1
UniProtKB entry
Q99999Swiss-Prot
Cellular location
Golgi apparatus membrane
Residues / weight
423 residues · 48,764 Da
Also known as
2.8.2.11 · 3'-phosphoadenosine-5'-phosphosulfate:GalCer sulfotransferase · 3'-phosphoadenylylsulfate:galactosylceramide 3'-sulfotransferase · Cerebroside sulfotransferase · CST

Resolves to

Protein
UniProtQ99999UniProt nameG3ST1_HUMAN
Gene
HGNCHGNC:24240NCBI Gene9514GeneCardsGAL3ST1
Pharmacology
KEGGhsa:9514
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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12GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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1+ReferenceStructured and connected to the statements they support
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Which compounds in development act on Galactosylceramide sulfotransferase, and which indications are they being tested in?

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