Cyclin-dependent kinase 19

BE0018995ProteinHumansCDK19

Component of the Mediator complex, a transcriptional coactivator required for regulated expression of nearly all RNA polymerase II-dependent genes. It is acted on by 2 drugs in DrugBank.

Gene name
CDK19
UniProtKB entry
Q9BWU1Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
502 residues · 56,802 Da
Also known as
2.7.11.22 · CDC2-related protein kinase 6 · CDC2L6 · CDK11 · Cell division cycle 2-like protein kinase 6

Resolves to

Protein
UniProtQ9BWU1UniProt nameCDK19_HUMAN
Gene
HGNCHGNC:19338NCBI Gene23097GeneCardsCDK19
Pharmacology
IUPHAR/GtoPdb1972KEGGhsa:23097
Drugs

What you can answer from here — as of September 03, 2024

2DrugsApproved to experimental, with action, bond type and pharmacological action
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1Pfam domainDomain architecture mapped to Pfam families and clans
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5+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Cyclin-dependent kinase 19, and which indications are they being tested in?

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