C-type lectin domain family 7 member A

BE0019143ProteinHumansCLEC7A

Lectin that functions as a pattern recognizing receptor (PRR) specific for beta-1,3-linked and beta-1,6-linked glucans, which constitute cell wall constituents from pathogenic bacteria and fungi (PubMed:11567029, PubMed:12423684). It is acted on by 2 drugs in DrugBank.

Gene name
CLEC7A
UniProtKB entry
Q9BXN2Swiss-Prot
Cellular location
Cell membrane
Residues / weight
247 residues · 27,627 Da
Also known as
Beta-glucan receptor · BGR · C-type lectin superfamily member 12 · CLECSF12 · DC-associated C-type lectin 1

Resolves to

Protein
UniProtQ9BXN2UniProt nameCLC7A_HUMAN
Gene
HGNCHGNC:14558NCBI Gene64581GeneCardsCLEC7A
Pharmacology
KEGGhsa:64581
Drugs

What you can answer from here — as of September 03, 2024

2DrugsApproved to experimental, with action, bond type and pharmacological action
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54GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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6+ReferencesStructured and connected to the statements they support
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Which compounds in development act on C-type lectin domain family 7 member A, and which indications are they being tested in?

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