Fructosamine-3-kinase

BE0019655ProteinHumansFN3K

Fructosamine-3-kinase involved in protein deglycation by mediating phosphorylation of fructoselysine residues on glycated proteins, to generate fructoselysine-3 phosphate (PubMed:11016445, PubMed:11522682, PubMed:11975663). It is acted on by 1 drug in DrugBank.

Gene name
FN3K
UniProtKB entry
Q9H479Swiss-Prot
Residues / weight
309 residues · 35,171 Da
Also known as
2.7.1.171 · Protein-psicosamine 3-kinase FN3K · Protein-ribulosamine 3-kinase FN3K

Resolves to

Protein
UniProtQ9H479UniProt nameFN3K_HUMAN
Gene
HGNCHGNC:24822NCBI Gene64122GeneCardsFN3K
Pharmacology
KEGGhsa:64122
Structure
PDB8UE1PDB9CX8PDB9CXM
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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9GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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1+ReferenceStructured and connected to the statements they support
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Which approved drugs act on Fructosamine-3-kinase, how selective are they, and which programs against it are still in active trials?

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