Ubiquitin-conjugating enzyme E2 T

BE0019778ProteinHumansUBE2T

Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. It is acted on by 1 drug in DrugBank.

Gene name
UBE2T
UniProtKB entry
Q9NPD8Swiss-Prot
Cellular location
Nucleus
Residues / weight
197 residues · 22,521 Da
Also known as
2.3.2.23 · Cell proliferation-inducing gene 50 protein · E2 ubiquitin-conjugating enzyme T · Ubiquitin carrier protein T · Ubiquitin-protein ligase T

Resolves to

Protein
UniProtQ9NPD8UniProt nameUBE2T_HUMAN
Gene
HGNCHGNC:25009NCBI Gene29089GeneCardsUBE2T
Pharmacology
KEGGhsa:29089
Structure
PDB1YH2PDB4CCGPDB5NGZ
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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17GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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1+ReferenceStructured and connected to the statements they support
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Which compounds in development act on Ubiquitin-conjugating enzyme E2 T, and which indications are they being tested in?

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