Bcl-2-like protein 10

BE0019838ProteinHumansBCL2L10

Promotes cell survival by suppressing apoptosis induced by BAX but not BAK (PubMed:11278245, PubMed:11689480). It is acted on by 1 drug in DrugBank.

Gene name
BCL2L10
UniProtKB entry
Q9HD36Swiss-Prot
Cellular location
Mitochondrion
Residues / weight
204 residues · 23,204 Da
Also known as
Anti-apoptotic protein Boo · Anti-apoptotic protein NrH · Apoptosis regulator Bcl-B · BCL-B · Bcl2-L-10

Resolves to

Protein
UniProtQ9HD36UniProt nameB2L10_HUMAN
Gene
HGNCHGNC:993NCBI Gene10017GeneCardsBCL2L10
Pharmacology
KEGGhsa:10017
Structure
PDB4B4S
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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1Pfam domainDomain architecture mapped to Pfam families and clans
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4+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Bcl-2-like protein 10, and which indications are they being tested in?

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