Very long chain fatty acid elongase 6

BE0019860ProteinHumansELOVL6

Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. It is acted on by 1 drug in DrugBank.

Gene name
ELOVL6
UniProtKB entry
Q9H5J4Swiss-Prot
Cellular location
Endoplasmic reticulum membrane
Residues / weight
265 residues · 31,376 Da
Also known as
2.3.1.199 · 3-keto acyl-CoA synthase ELOVL6 · Elongation of very long chain fatty acids protein 6 · ELOVL FA elongase 6 · ELOVL fatty acid elongase 6

Resolves to

Protein
UniProtQ9H5J4UniProt nameELOV6_HUMAN
Gene
HGNCHGNC:15829NCBI Gene79071GeneCardsELOVL6
Pharmacology
KEGGhsa:79071
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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13GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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1+ReferenceStructured and connected to the statements they support
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Which compounds in development act on Very long chain fatty acid elongase 6, and which indications are they being tested in?

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