Nicotinamide riboside kinase 2

BE0019876ProteinHumansNMRK2

Catalyzes the phosphorylation of nicotinamide riboside (NR) and nicotinic acid riboside (NaR) to form nicotinamide mononucleotide (NMN) and nicotinic acid mononucleotide (NaMN). It is acted on by 1 drug in DrugBank.

Gene name
NMRK2
UniProtKB entry
Q9NPI5Swiss-Prot
Residues / weight
230 residues · 26,045 Da
Also known as
2.7.1.22 · Integrin beta-1-binding protein 3 · ITGB1BP3 · MIBP · Muscle integrin-binding protein

Resolves to

Protein
UniProtQ9NPI5UniProt nameNRK2_HUMAN
Gene
HGNCHGNC:17871NCBI Gene27231GeneCardsNMRK2
Pharmacology
KEGGhsa:27231
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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6GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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3+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Nicotinamide riboside kinase 2, how selective are they, and which programs against it are still in active trials?

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