Solute carrier family 52, riboflavin transporter, member 3

BE0019983ProteinHumansSLC52A3

Plasma membrane transporter mediating the uptake by cells of the water soluble vitamin B2/riboflavin that plays a key role in biochemical oxidation-reduction reactions of the carbohydrate, lipid, and amino acid metabolism (PubMed:20463145, PubMed:22273710, PubMed:24264046, PubMed:27702554). It is acted on by 1 drug in DrugBank.

Gene name
SLC52A3
UniProtKB entry
Q9NQ40Swiss-Prot
Cellular location
Apical cell membrane
Residues / weight
469 residues · 50,805 Da
Also known as
C20orf54 · hRFT2 · RFT2 · RFVT3 · Riboflavin transporter 2

Resolves to

Protein
UniProtQ9NQ40UniProt nameS52A3_HUMAN
Gene
HGNCHGNC:16187NCBI Gene113278GeneCardsSLC52A3
Pharmacology
KEGGhsa:113278
Structure
PDB8XSN
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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9GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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1+ReferenceStructured and connected to the statements they support
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Which compounds in development act on Solute carrier family 52, riboflavin transporter, member 3, and which indications are they being tested in?

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