Tumor necrosis factor receptor superfamily member 12A

BE0020009ProteinHumansTNFRSF12A

Receptor for TNFSF12/TWEAK. It is acted on by 2 drugs in DrugBank.

Gene name
TNFRSF12A
UniProtKB entry
Q9NP84Swiss-Prot
Cellular location
Membrane
Residues / weight
129 residues · 13,911 Da
Also known as
FGF-inducible 14 · Fibroblast growth factor-inducible immediate-early response protein 14 · FN14 · Tweak-receptor · TweakR

Resolves to

Protein
UniProtQ9NP84UniProt nameTNR12_HUMAN
Gene
HGNCHGNC:18152NCBI Gene51330GeneCardsTNFRSF12A
Pharmacology
KEGGhsa:51330
Structure
PDB2EQPPDB2KMZPDB2RPJ
Drugs

What you can answer from here — as of September 03, 2024

2DrugsApproved to experimental, with action, bond type and pharmacological action
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3GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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2+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Tumor necrosis factor receptor superfamily member 12A, and which indications are they being tested in?

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