Interleukin-17 receptor B

BE0020027ProteinHumansIL17RB

Receptor for the pro-inflammatory cytokines IL17B and IL17E. It is acted on by 1 drug in DrugBank.

Gene name
IL17RB
UniProtKB entry
Q9NRM6Swiss-Prot
Cellular location
Cell membrane
Residues / weight
502 residues · 55,884 Da
Also known as
CRL4 · Cytokine receptor-like 4 · EVI27 · IL-17 receptor B · IL-17 receptor homolog 1

Resolves to

Protein
UniProtQ9NRM6UniProt nameI17RB_HUMAN
Gene
HGNCHGNC:18015NCBI Gene55540GeneCardsIL17RB
Pharmacology
KEGGhsa:55540
Structure
PDB7UWJPDB7UWKPDB7UWL
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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1+ReferenceStructured and connected to the statements they support
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Which approved drugs act on Interleukin-17 receptor B, how selective are they, and which programs against it are still in active trials?

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