Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1

BE0020167ProteinHumansC1GALT1

Glycosyltransferase that generates the core 1 O-glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins (PubMed:11677243). It is acted on by 1 drug in DrugBank.

Gene name
C1GALT1
UniProtKB entry
Q9NS00Swiss-Prot
Cellular location
Membrane
Residues / weight
363 residues · 42,203 Da
Also known as
2.4.1.122 · B3Gal-T8 · Beta-1,3-galactosyltransferase · C1GalT1 · Core 1 beta1,3-galactosyltransferase 1

Resolves to

Protein
UniProtQ9NS00UniProt nameC1GLT_HUMAN
Gene
HGNCHGNC:24337NCBI Gene56913GeneCardsC1GALT1
Pharmacology
KEGGhsa:56913
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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1Pfam domainDomain architecture mapped to Pfam families and clans
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1+ReferenceStructured and connected to the statements they support
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Which compounds in development act on Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1, and which indications are they being tested in?

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