Pyroglutamyl-peptidase 1

BE0020171ProteinHumansPGPEP1

Removes 5-oxoproline from various penultimate amino acid residues except L-proline. It is acted on by 1 drug in DrugBank.

Gene name
PGPEP1
UniProtKB entry
Q9NXJ5Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
209 residues · 23,138 Da
Also known as
3.4.19.3 · 5-oxoprolyl-peptidase · PAP-I · PGP-I · PGPI

Resolves to

Protein
UniProtQ9NXJ5UniProt namePGPI_HUMAN
Gene
HGNCHGNC:13568NCBI Gene54858GeneCardsPGPEP1
Pharmacology
KEGGhsa:54858
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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5GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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1+ReferenceStructured and connected to the statements they support
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Which compounds in development act on Pyroglutamyl-peptidase 1, and which indications are they being tested in?

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