Pyroglutamyl-peptidase 1

BE0020171ProteinHumansPGPEP1

Removes 5-oxoproline from various penultimate amino acid residues except L-proline. It is acted on by 1 drug in DrugBank.

Gene name
PGPEP1
UniProtKB entry
Q9NXJ5Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
209 residues · 23,138 Da
Also known as
3.4.19.3 · 5-oxoprolyl-peptidase · PAP-I · PGP-I · PGPI

Resolves to

Protein
UniProtQ9NXJ5UniProt namePGPI_HUMAN
Gene
HGNCHGNC:13568NCBI Gene54858GeneCardsPGPEP1
Pharmacology
KEGGhsa:54858
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
Sign in
1Pfam domainDomain architecture mapped to Pfam families and clans
Sign in
1+ReferenceStructured and connected to the statements they support
Sign in

Which compounds in development act on Pyroglutamyl-peptidase 1, and which indications are they being tested in?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In