Dipeptidyl peptidase 3

BE0020247ProteinHumansDPP3

Cleaves and degrades bioactive peptides, including angiotensin, Leu-enkephalin and Met-enkephalin (PubMed:1515063, PubMed:3233187). It is acted on by 1 drug in DrugBank.

Gene name
DPP3
UniProtKB entry
Q9NY33Swiss-Prot
Cellular location
Cytoplasm, cytosol
Residues / weight
737 residues · 82,588 Da
Also known as
3.4.14.4 · Dipeptidyl aminopeptidase III · Dipeptidyl arylamidase III · Dipeptidyl peptidase III · DPP III

Resolves to

Protein
UniProtQ9NY33UniProt nameDPP3_HUMAN
Gene
HGNCHGNC:3008NCBI Gene10072GeneCardsDPP3
Pharmacology
KEGGhsa:10072
Structure
PDB3FVYPDB3T6BPDB3T6J
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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1Pfam domainDomain architecture mapped to Pfam families and clans
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7+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Dipeptidyl peptidase 3, and which indications are they being tested in?

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