DNA polymerase delta subunit 4

BE0020436ProteinHumansPOLD4

As a component of the tetrameric DNA polymerase delta complex (Pol-delta4), plays a role in high fidelity genome replication and repair. It is acted on by 1 drug in DrugBank.

Gene name
POLD4
UniProtKB entry
Q9HCU8Swiss-Prot
Cellular location
Nucleus
Residues / weight
107 residues · 12,433 Da
Also known as
DNA polymerase delta subunit p12 · POLDS

Resolves to

Protein
UniProtQ9HCU8UniProt nameDPOD4_HUMAN
Gene
HGNCHGNC:14106NCBI Gene57804GeneCardsPOLD4
Pharmacology
KEGGhsa:57804
Structure
PDB6HVOPDB6S1MPDB6S1N
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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5GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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1+ReferenceStructured and connected to the statements they support
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Which approved drugs act on DNA polymerase delta subunit 4, how selective are they, and which programs against it are still in active trials?

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