Interleukin-20

BE0020481ProteinHumansIL20

Pro-inflammatory and angiogenic cytokine mainly secreted by monocytes and skin keratinocytes that plays crucial roles in immune responses, regulation of inflammatory responses, hemopoiesis, as well as epidermal cell and keratinocyte differentiation (PubMed:17277128, PubMed:34403503). It is acted on by 1 drug in DrugBank.

Gene name
IL20
UniProtKB entry
Q9NYY1Swiss-Prot
Cellular location
Secreted
Residues / weight
176 residues · 20,072 Da
Also known as
Cytokine Zcyto10 · IL-20 · ZCYTO10

Resolves to

Protein
UniProtQ9NYY1UniProt nameIL20_HUMAN
Gene
HGNCHGNC:6002NCBI Gene50604GeneCardsIL20
Pharmacology
KEGGhsa:50604
Structure
PDB4DOH
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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1GO termFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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1+ReferenceStructured and connected to the statements they support
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Which compounds in development act on Interleukin-20, and which indications are they being tested in?

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