Double homeobox protein 4

BE0020504ProteinHumansDUX4

Transcription factor that is selectively and transiently expressed in cleavage-stage embryos (PubMed:28459457). It is acted on by 1 drug in DrugBank.

Gene name
DUX4
UniProtKB entry
Q9UBX2Swiss-Prot
Cellular location
Nucleus
Residues / weight
424 residues · 44,940 Da
Also known as
Double homeobox protein 10 · DUX10

Resolves to

Protein
UniProtQ9UBX2UniProt nameDUX4_HUMAN
Gene
HGNCHGNC:50800NCBI Gene100288687GeneCardsDUX4
Pharmacology
KEGGhsa:100288687
Structure
PDB5Z2SPDB5Z2TPDB5Z6Z
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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1Pfam domainDomain architecture mapped to Pfam families and clans
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1+ReferenceStructured and connected to the statements they support
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Which compounds in development act on Double homeobox protein 4, and which indications are they being tested in?

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