Lysophosphatidic acid receptor 3

Details

Name
Lysophosphatidic acid receptor 3
Kind
protein
Synonyms
  • EDG7
  • LPA receptor 3
  • LPA-3
  • LPA3
  • Lysophosphatidic acid receptor Edg-7
Gene Name
LPAR3
UniProtKB Entry
Q9UBY5Swiss-Prot
Organism
Humans
NCBI Taxonomy ID
9606
Amino acid sequence
>lcl|BSEQ0063407|Lysophosphatidic acid receptor 3
MNECHYDKHMDFFYNRSNTDTVDDWTGTKLVIVLCVGTFFCLFIFFSNSLVIAAVIKNRK
FHFPFYYLLANLAAADFFAGIAYVFLMFNTGPVSKTLTVNRWFLRQGLLDSSLTASLTNL
LVIAVERHMSIMRMRVHSNLTKKRVTLLILLVWAIAIFMGAVPTLGWNCLCNISACSSLA
PIYSRSYLVFWTVSNLMAFLIMVVVYLRIYVYVKRKTNVLSPHTSGSISRRRTPMKLMKT
VMTVLGAFVVCWTPGLVVLLLDGLNCRQCGVQHVKRWFLLLALLNSVVNPIIYSYKDEDM
YGTMKKMICCFSQENPERRPSRIPSTVLSRSDTGSQYIEDSISQGAVCNKSTS
Number of residues
353
Molecular Weight
40128.07
Theoretical pI
Not Available
GO Classification
Not Available
General Function
Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. May play a role in the development of ovarian cancer. Seems to be coupled to the G(i)/G(o) and G(q) families of heteromeric G proteins
Specific Function
G protein-coupled receptor activity
Pfam Domain Function
Signal Regions
Not Available
Transmembrane Regions
32-52 68-88 102-124 147-167 187-207 241-261 277-297
Cellular Location
Cell membrane
Gene sequence
Not Available
Chromosome Location
1
Locus
1p22.3
External Identifiers
ResourceLink
UniProtKB IDQ9UBY5
UniProtKB Entry NameLPAR3_HUMAN
GeneCard IDLPAR3
HGNC IDHGNC:14298
KEGG IDhsa:23566
IUPHAR/Guide To Pharmacology ID274
NCBI Gene ID23566
General References
Not Available

Associated Data

Drug Relations
DrugDrug groupPharmacological action?TypeActionsDetails
FipaxalparantinvestigationalyestargetmodulatorDetails