Lysophosphatidic acid receptor 3
Details
- Name
- Lysophosphatidic acid receptor 3
- Kind
- protein
- Synonyms
- EDG7
- LPA receptor 3
- LPA-3
- LPA3
- Lysophosphatidic acid receptor Edg-7
- Gene Name
- LPAR3
- UniProtKB Entry
- Q9UBY5Swiss-Prot
- Organism
- Humans
- NCBI Taxonomy ID
- 9606
- Amino acid sequence
>lcl|BSEQ0063407|Lysophosphatidic acid receptor 3 MNECHYDKHMDFFYNRSNTDTVDDWTGTKLVIVLCVGTFFCLFIFFSNSLVIAAVIKNRK FHFPFYYLLANLAAADFFAGIAYVFLMFNTGPVSKTLTVNRWFLRQGLLDSSLTASLTNL LVIAVERHMSIMRMRVHSNLTKKRVTLLILLVWAIAIFMGAVPTLGWNCLCNISACSSLA PIYSRSYLVFWTVSNLMAFLIMVVVYLRIYVYVKRKTNVLSPHTSGSISRRRTPMKLMKT VMTVLGAFVVCWTPGLVVLLLDGLNCRQCGVQHVKRWFLLLALLNSVVNPIIYSYKDEDM YGTMKKMICCFSQENPERRPSRIPSTVLSRSDTGSQYIEDSISQGAVCNKSTS
- Number of residues
- 353
- Molecular Weight
- 40128.07
- Theoretical pI
- Not Available
- GO Classification
- Not Available
- General Function
- Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. May play a role in the development of ovarian cancer. Seems to be coupled to the G(i)/G(o) and G(q) families of heteromeric G proteins
- Specific Function
- G protein-coupled receptor activity
- Pfam Domain Function
- 7tm_1 (PF00001)
- Signal Regions
- Not Available
- Transmembrane Regions
- 32-52 68-88 102-124 147-167 187-207 241-261 277-297
- Cellular Location
- Cell membrane
- Gene sequence
- Not Available
- Chromosome Location
- 1
- Locus
- 1p22.3
- External Identifiers
Resource Link UniProtKB ID Q9UBY5 UniProtKB Entry Name LPAR3_HUMAN GeneCard ID LPAR3 HGNC ID HGNC:14298 KEGG ID hsa:23566 IUPHAR/Guide To Pharmacology ID 274 NCBI Gene ID 23566 - General References
- Not Available
Associated Data
- Drug Relations
Drug Drug group Pharmacological action? Type Actions Details Fipaxalparant investigational yes target modulator Details