STEAP1 protein

BE0020568ProteinHumansSTEAP1

Does not function as a metalloreductase due to the absence of binding sites for the electron-donating substrate NADPH. It is acted on by 2 drugs in DrugBank.

Gene name
STEAP1
UniProtKB entry
Q9UHE8Swiss-Prot
Cellular location
Endosome membrane
Residues / weight
339 residues · 39,851 Da
Also known as
PRSS24 · Six-transmembrane epithelial antigen of prostate 1 · STEAP

Resolves to

Protein
UniProtQ9UHE8UniProt nameSTEA1_HUMAN
Gene
HGNCHGNC:11378NCBI Gene26872GeneCardsSTEAP1
Pharmacology
IUPHAR/GtoPdb3303KEGGhsa:26872
Structure
PDB6Y9BPDB8UCD
Drugs

What you can answer from here — as of September 03, 2024

2DrugsApproved to experimental, with action, bond type and pharmacological action
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1Pfam domainDomain architecture mapped to Pfam families and clans
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3+ReferencesStructured and connected to the statements they support
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Which compounds in development act on STEAP1 protein, and which indications are they being tested in?

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