Prenylcysteine oxidase 1

BE0020601ProteinHumansPCYOX1

Prenylcysteine oxidase that cleaves the thioether bond of prenyl-L-cysteines, such as farnesylcysteine and geranylgeranylcysteine (PubMed:10585463, PubMed:11078725, PubMed:12186880). It is acted on by 1 drug in DrugBank.

Gene name
PCYOX1
UniProtKB entry
Q9UHG3Swiss-Prot
Cellular location
Lysosome
Residues / weight
505 residues · 56,640 Da
Also known as
1.8.3.5 · KIAA0908 · PCL1 · Prenylcysteine lyase

Resolves to

Protein
UniProtQ9UHG3UniProt namePCYOX_HUMAN
Gene
HGNCHGNC:20588NCBI Gene51449GeneCardsPCYOX1
Pharmacology
KEGGhsa:51449
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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8GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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3+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Prenylcysteine oxidase 1, and which indications are they being tested in?

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