Carboxypeptidase A4

BE0020784ProteinHumansCPA4

Metalloprotease that cleaves hydrophobic C-terminal residues with a preference for -Phe, -Leu, -Ile, -Met, -Tyr and -Val (PubMed:20385563). It is acted on by 1 drug in DrugBank.

Gene name
CPA4
UniProtKB entry
Q9UI42Swiss-Prot
Cellular location
Secreted
Residues / weight
421 residues · 47,351 Da
Also known as
3.4.17.- · Carboxypeptidase A3 · CPA3

Resolves to

Protein
UniProtQ9UI42UniProt nameCBPA4_HUMAN
Gene
HGNCHGNC:15740NCBI Gene51200GeneCardsCPA4
Pharmacology
KEGGhsa:51200
Structure
PDB2BO9PDB2BOAPDB2PCU
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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6GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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1+ReferenceStructured and connected to the statements they support
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Which compounds in development act on Carboxypeptidase A4, and which indications are they being tested in?

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