Dynein axonemal intermediate chain 1

BE0020794ProteinHumansDNAI1

Component of dynein, a family of motor proteins essential for movement along microtubules (By similarity). It is acted on by 1 drug in DrugBank.

Gene name
DNAI1
UniProtKB entry
Q9UI46Swiss-Prot
Cellular location
Dynein axonemal particle
Residues / weight
699 residues · 79,282 Da
Also known as
Axonemal dynein intermediate chain 1

Resolves to

Protein
UniProtQ9UI46UniProt nameDNAI1_HUMAN
Gene
HGNCHGNC:2954NCBI Gene27019GeneCardsDNAI1
Pharmacology
KEGGhsa:27019
Structure
PDB8J07
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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15GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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3+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Dynein axonemal intermediate chain 1, and which indications are they being tested in?

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