Sarcosine dehydrogenase, mitochondrial

BE0021033ProteinHumansSARDH

Catalyzes the last step of the oxidative degradation of choline to glycine. It is acted on by 1 drug in DrugBank.

Gene name
SARDH
UniProtKB entry
Q9UL12Swiss-Prot
Cellular location
Mitochondrion matrix
Residues / weight
918 residues · 101,036 Da
Also known as
1.5.8.3 · BPR-2 · DMGDHL1 · SarDH

Resolves to

Protein
UniProtQ9UL12UniProt nameSARDH_HUMAN
Gene
HGNCHGNC:10536NCBI Gene1757GeneCardsSARDH
Pharmacology
KEGGhsa:1757
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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4Pfam domainsDomain architecture mapped to Pfam families and clans
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2+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Sarcosine dehydrogenase, mitochondrial, and which indications are they being tested in?

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