Tumor necrosis factor receptor superfamily member EDAR

BE0021253ProteinHumansEDAR

Receptor for EDA isoform A1, but not for EDA isoform A2. It is acted on by 1 drug in DrugBank.

Gene name
EDAR
UniProtKB entry
Q9UNE0Swiss-Prot
Cellular location
Membrane
Residues / weight
448 residues · 48,582 Da
Also known as
Anhidrotic ectodysplasin receptor 1 · DL · Downless homolog · Ectodermal dysplasia receptor · Ectodysplasin-A receptor

Resolves to

Protein
UniProtQ9UNE0UniProt nameEDAR_HUMAN
Gene
HGNCHGNC:2895NCBI Gene10913GeneCardsEDAR
Pharmacology
KEGGhsa:10913
Structure
PDB7X9G
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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1Pfam domainDomain architecture mapped to Pfam families and clans
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1+ReferenceStructured and connected to the statements they support
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Which compounds in development act on Tumor necrosis factor receptor superfamily member EDAR, and which indications are they being tested in?

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