Insulin receptor substrate 2

BE0021286ProteinHumansIRS2

Signaling adapter protein that participates in the signal transduction from two prominent receptor tyrosine kinases, insulin receptor/INSR and insulin-like growth factor I receptor/IGF1R (PubMed:25879670). It is acted on by 1 drug in DrugBank.

Gene name
IRS2
UniProtKB entry
Q9Y4H2Swiss-Prot
Cellular location
Cytoplasm, cytosol
Residues / weight
1,338 residues · 137,333 Da
Also known as
IRS-2

Resolves to

Pharmacology

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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1+ReferenceStructured and connected to the statements they support
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Which compounds in development act on Insulin receptor substrate 2, and which indications are they being tested in?

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