Endothelial lipase

BE0021370ProteinHumansLIPG

Exerts both phospholipase and triglyceride lipase activities (PubMed:10192396, PubMed:10318835, PubMed:12032167). It is acted on by 1 drug in DrugBank.

Gene name
LIPG
UniProtKB entry
Q9Y5X9Swiss-Prot
Cellular location
Secreted
Residues / weight
500 residues · 56,794 Da
Also known as
3.1.1.3 · EDL · EL · Endothelial cell-derived lipase · Phospholipase A1

Resolves to

Protein
UniProtQ9Y5X9UniProt nameLIPG_HUMAN
Gene
HGNCHGNC:6623NCBI Gene9388GeneCardsLIPG
Pharmacology
IUPHAR/GtoPdb2591KEGGhsa:9388
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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19GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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1+ReferenceStructured and connected to the statements they support
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Which compounds in development act on Endothelial lipase, and which indications are they being tested in?

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