tRNA-dihydrouridine(20a/20b) synthase [NAD(P)+]-like

BE0022092ProteinHumansDUS4L

Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. It is acted on by 1 drug in DrugBank.

Gene name
DUS4L
UniProtKB entry
O95620Swiss-Prot
Residues / weight
317 residues · 35,816 Da
Also known as
1.3.1.90 · pp35 · tRNA-dihydrouridine synthase 4-like

Resolves to

Protein
UniProtO95620UniProt nameDUS4L_HUMAN
Gene
HGNCHGNC:21517NCBI Gene11062GeneCardsDUS4L
Pharmacology
KEGGhsa:11062
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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5GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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2+ReferencesStructured and connected to the statements they support
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Which compounds in development act on tRNA-dihydrouridine(20a/20b) synthase [NAD(P)+]-like, and which indications are they being tested in?

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