Ketosamine-3-kinase

BE0023133ProteinHumansFN3KRP

Ketosamine-3-kinase involved in protein deglycation by mediating phosphorylation of ribuloselysine and psicoselysine on glycated proteins, to generate ribuloselysine-3 phosphate and psicoselysine-3 phosphate, respectively (PubMed:14633848, PubMed:15137908). It is acted on by 1 drug in DrugBank.

Gene name
FN3KRP
UniProtKB entry
Q9HA64Swiss-Prot
Residues / weight
309 residues · 34,412 Da
Also known as
2.7.1.172 · FN3K-related protein · FN3K-RP · Fructosamine-3-kinase-related protein · Protein-psicosamine 3-kinase FN3KRP

Resolves to

Protein
UniProtQ9HA64UniProt nameKT3K_HUMAN
Gene
HGNCHGNC:25700NCBI Gene79672GeneCardsFN3KRP
Pharmacology
KEGGhsa:79672
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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1+ReferenceStructured and connected to the statements they support
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Which approved drugs act on Ketosamine-3-kinase, how selective are they, and which programs against it are still in active trials?

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