Aminopeptidase B

BE0023564ProteinHumansRNPEP

Exopeptidase which selectively removes arginine and/or lysine residues from the N-terminus of several peptide substrates including Arg(0)-Leu-enkephalin, Arg(0)-Met-enkephalin and Arg(-1)-Lys(0)-somatostatin-14. It is acted on by 1 drug in DrugBank.

Gene name
RNPEP
UniProtKB entry
Q9H4A4Swiss-Prot
Cellular location
Secreted
Residues / weight
650 residues · 72,595 Da
Also known as
3.4.11.6 · AP-B · APB · Arginine aminopeptidase · Arginyl aminopeptidase

Resolves to

Protein
UniProtQ9H4A4UniProt nameAMPB_HUMAN
Gene
HGNCHGNC:10078NCBI Gene6051GeneCardsRNPEP
Pharmacology
KEGGhsa:6051
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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9GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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2+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Aminopeptidase B, and which indications are they being tested in?

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