Delta(14)-sterol reductase ERG24

BE0027701ProteinBaker's yeastERG24

Delta(14)-sterol reductase; part of the third module of ergosterol biosynthesis pathway that includes the late steps of the pathway (PubMed:1418625, PubMed:8125337). It is acted on by 2 drugs in DrugBank.

Gene name
ERG24
UniProtKB entry
P32462Swiss-Prot
Cellular location
Membrane
Residues / weight
438 residues · 50,615 Da
Also known as
1.3.1.70 · C-14 sterol reductase ERG24 · Ergosterol biosynthetic protein 24 · Sterol C14-reductase ERG24

Resolves to

Protein
UniProtP32462UniProt nameERG24_YEAST
Gene
NCBI Gene855441
Pharmacology
KEGGsce:YNL280C
Drugs

What you can answer from here — as of December 17, 2025

2DrugsApproved to experimental, with action, bond type and pharmacological action
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5GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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3+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Delta(14)-sterol reductase ERG24, how selective are they, and which programs against it are still in active trials?

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