C-8 sterol isomerase ERG2

BE0027702ProteinBaker's yeastERG2

C-8 sterol isomerase; part of the third module of ergosterol biosynthesis pathway that includes the late steps of the pathway (Ref.5). It is acted on by 1 drug in DrugBank.

Gene name
ERG2
UniProtKB entry
P32352Swiss-Prot
Cellular location
Endoplasmic reticulum membrane
Residues / weight
222 residues · 24,895 Da
Also known as
5.-.-.- · Delta-8--delta-7 sterol isomerase ERG2 · Ergosterol biosynthetic protein 2

Resolves to

Protein
UniProtP32352UniProt nameERG2_YEAST
Gene
NCBI Gene855242
Pharmacology
KEGGsce:YMR202W
Drugs

What you can answer from here — as of December 17, 2025

1DrugApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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1+ReferenceStructured and connected to the statements they support
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Which approved drugs act on C-8 sterol isomerase ERG2, how selective are they, and which programs against it are still in active trials?

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