Acetylcholine receptor subunit alpha-type acr-16

BE0027703ProteinCaenorhabditis elegansacr-16

After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane (By similarity). It is acted on by 2 drugs in DrugBank.

Gene name
acr-16
UniProtKB entry
P48180Swiss-Prot
Cellular location
Postsynaptic cell membrane
Residues / weight
498 residues · 57,168 Da
Also known as
Ce21

Resolves to

What you can answer from here — as of December 17, 2025

2DrugsApproved to experimental, with action, bond type and pharmacological action
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13GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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3+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Acetylcholine receptor subunit alpha-type acr-16, and which indications are they being tested in?

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