Interferon-stimulated gene 20 kDa protein

BE0001938ProteinHumansISG20

Interferon-induced antiviral exoribonuclease that acts mainly on single-stranded RNA (PubMed:11401564, PubMed:12594219, PubMed:16033969). It is acted on by 1 drug in DrugBank.

Gene name
ISG20
UniProtKB entry
Q96AZ6Swiss-Prot
Cellular location
Nucleus
Residues / weight
181 residues · 20,363 Da
Also known as
3.1.13.1 · Estrogen-regulated transcript 45 protein · HEM45 · Promyelocytic leukemia nuclear body-associated protein ISG20

Resolves to

Protein
UniProtQ96AZ6UniProt nameISG20_HUMAN
Gene
HGNCHGNC:6130NCBI Gene3669GenBank6759541GeneCardsISG20
Pharmacology
KEGGhsa:3669
Structure
PDB1WLJPDB7UGB
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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1Clinical trialTrials of drugs acting on it, by phase and status
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15GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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13+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Interferon-stimulated gene 20 kDa protein, and which indications are they being tested in?

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