HLA class II histocompatibility antigen, DQ alpha 2 chain

BE0002122ProteinHumansHLA-DQA2

Binds peptides derived from antigens that access the endocytic route of antigen presenting cells (APC) and presents them on the cell surface for recognition by the CD4 T-cells.

Gene name
HLA-DQA2
UniProtKB entry
P01906Swiss-Prot
Cellular location
Cell membrane
Residues / weight
255 residues · 28,033 Da
Also known as
DX alpha chain · HLA class II histocompatibility antigen, DQ(6) alpha chain · HLA-DQA1 · HLA-DXA · MHC class II DQA2

Resolves to

Protein
UniProtP01906UniProt nameDQA2_HUMAN
Gene
HGNCHGNC:4943NCBI Gene3118GenBank493166GeneCardsHLA-DQA2
Pharmacology
KEGGhsa:3118

What you can answer from here — as of September 07, 2019

7GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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14+ReferencesStructured and connected to the statements they support
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Which compounds in development act on HLA class II histocompatibility antigen, DQ alpha 2 chain, and which indications are they being tested in?

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