- Nucleoside Deaminases
- Accession Number
Catalyze the hydrolysis of nucleosides with the elimination of ammonia.
Drug Drug Description Pegademase A modified form of bovine adenosine deaminase used to treat adenosine deaminase deficiency, a condition which leads to the formation of adenosine metabolites which are cytotoxic to lymphocytes. Vocimagene amiretrorepvec Vocimagene amiretrorepvec is under investigation in clinical trial NCT02576665 (A Study of Toca 511, a Retroviral Replicating Vector, Combined With Toca FC in Patients With Solid Tumors or Lymphoma (Toca...
- Drugs & Drug Targets
Drug Target Type Pegademase Adenosine target Pegademase Growth factor receptor-bound protein 2 target