Nucleoside Deaminases
- Name
- Nucleoside Deaminases
- Accession Number
- DBCAT000161
- Description
Catalyze the hydrolysis of nucleosides with the elimination of ammonia.
- Drugs
Drug Drug Description Pegademase A modified form of bovine adenosine deaminase used to treat adenosine deaminase deficiency, a condition which leads to the formation of adenosine metabolites which are cytotoxic to lymphocytes. Elapegademase A recombinant adenosine deaminase used to treat adenosine deaminase severe combined immune deficiency. Vocimagene amiretrorepvec Vocimagene amiretrorepvec is under investigation in clinical trial NCT02576665 (A Study of Toca 511, a Retroviral Replicating Vector, Combined With Toca FC in Patients With Solid Tumors or Lymphoma (Toca... - Drugs & Drug Targets
Drug Target Type Pegademase Adenosine target Pegademase Growth factor receptor-bound protein 2 target Elapegademase Adenosine target