Nucleoside Deaminases

Name
Nucleoside Deaminases
Accession Number
DBCAT000161
Description

Catalyze the hydrolysis of nucleosides with the elimination of ammonia.

Drugs
DrugDrug Description
PegademaseA modified form of bovine adenosine deaminase used to treat adenosine deaminase deficiency, a condition which leads to the formation of adenosine metabolites which are cytotoxic to lymphocytes.
Vocimagene amiretrorepvecVocimagene amiretrorepvec is under investigation in clinical trial NCT02576665 (A Study of Toca 511, a Retroviral Replicating Vector, Combined With Toca FC in Patients With Solid Tumors or Lymphoma (Toca...
Drugs & Drug Targets
DrugTargetType
PegademaseAdenosinetarget
PegademaseGrowth factor receptor-bound protein 2target