Phthalic Acids

Name
Phthalic Acids
Accession Number
DBCAT000723
Description

A group of compounds that has the general structure of a dicarboxylic acid-substituted benzene ring. The ortho-isomer is used in dye manufacture. (Dorland, 28th ed)

Drugs
DrugDrug Description
LenalidomideA thalidomide derivative used to treat multiple myeloma and anemia in low to intermediate risk myelodysplastic syndrome.
DibutylphthalateNot Annotated
ThalidomideA medication used to treat newly diagnosed multiple myeloma and erythema nodosum leprosum.
PomalidomideA thalidomide analogue used in combination with dexamethasone to treat patients with multiple myeloma.
CC-220CC-220 has been used in trials studying the treatment of Systemic Lupus Erythematosus.
CEP-9722CEP-9722 is under investigation in clinical trial NCT01345357 (Study of CEP-9722 in Combination With Gemcitabine and Cisplatin in Patients With Advanced Solid Tumors or Mantle Cell Lymphoma).
Drugs & Drug Targets
DrugTargetType
LenalidomideProstaglandin G/H synthase 2target
LenalidomideTumor necrosis factor ligand superfamily member 11target
LenalidomideCadherin-5target
LenalidomideProtein cereblontarget
LenalidomideP-glycoprotein 1transporter
ThalidomideTumor necrosis factortarget
ThalidomideNuclear factor NF-kappa-B p105 subunittarget
ThalidomideProstaglandin G/H synthase 2target
ThalidomideCytochrome P450 2C19enzyme
ThalidomideCytochrome P450 2C9enzyme
ThalidomideProstaglandin G/H synthase 1enzyme
ThalidomideProstaglandin G/H synthase 2enzyme
ThalidomideCytochrome P450 3A5enzyme
ThalidomideFibroblast growth factor receptor 2target
ThalidomideDNAtarget
ThalidomideProtein cereblontarget
Thalidomidealpha1-acid glycoproteintarget
PomalidomideCytochrome P450 1A2enzyme
PomalidomideCytochrome P450 3A4enzyme
PomalidomideP-glycoprotein 1transporter
PomalidomideProtein cereblontarget
PomalidomideTumor necrosis factortarget
PomalidomideProstaglandin G/H synthase 2target