Name
Valerates
Accession Number
DBCAT000732
Description

Derivatives of valeric acid, including its salts and esters.

Drugs
DrugDrug Description
Valproic acidAn anticonvulsant used to control complex partial seizures and both simple and complex absence seizures.
RidogrelUsed as an adjunctive therapy to induce thrombolysis in patients suffering acute myocardial infarction.
GemfibrozilA lipid regulator that is used in the reduction of serum triglyceride levels in high-risk patients with hyperlipidemia.
Isovaleric AcidNot Available
5-phenylpentanoic acidNot Available
alpha-KetoisovalerateNot Available
ValpromideA valproic acid derivative used to treat epilepsy and as adjunct therapy for psychomotor agitation, depression, and manic episodes of bipolar disorder.
DexloxiglumideFor the treatment of Irritable Bowel Syndrome (IBS) and Gastroesophageal Reflux Disease (GERD).
EmricasanInvestigated for use/treatment in hepatitis (viral, C), liver disease, and transplantation (organ or tissue).
DP-VPAInvestigated for use/treatment in bipolar disorders, epilepsy, and migraine and cluster headaches.
FiboflaponInvestigated for use/treatment in inflammatory disorders (unspecified).
MonensinMonensin is a polyether isolated from Streptomyces cinnamonensis that presents antibiotic properties. It is widely used in ruminant animal feeds.
KH064Not Available
alpha-Keto-beta-methylvaleric acidNot Annotated
Drugs & Drug Targets
DrugTargetType
Valproic acidHistone deacetylase 9target
Valproic acidShort/branched chain specific acyl-CoA dehydrogenase, mitochondrialtarget
Valproic acidCytochrome P450 2A6enzyme
Valproic acidCytochrome P450 2B6enzyme
Valproic acidCytochrome P450 2C9enzyme
Valproic acidSolute carrier family 22 member 5transporter
Valproic acidSolute carrier family 22 member 6transporter
Valproic acidSolute carrier family 22 member 8transporter
Valproic acidMonocarboxylate transporter 1transporter
Valproic acidSolute carrier family 22 member 7transporter
Valproic acidCytochrome P450 3A5enzyme
Valproic acidUDP-glucuronosyltransferase 1-9enzyme
Valproic acidProstaglandin G/H synthase 1enzyme
Valproic acidCytochrome P450 1A2enzyme
Valproic acidCytochrome P450 2C19enzyme
Valproic acidCytochrome P450 3A4enzyme
Valproic acidUDP-glucuronosyltransferase 1-4enzyme
Valproic acidUDP-glucuronosyltransferase 1-8enzyme
Valproic acidUDP-glucuronosyltransferase 1-10enzyme
Valproic acidUDP-glucuronosyltransferase 1-6enzyme
Valproic acidUDP-glucuronosyltransferase 1-3enzyme
Valproic acidUDP-glucuronosyltransferase 2B7enzyme
Valproic acidUDP-glucuronosyltransferase 2B15enzyme
Valproic acid2-oxoglutarate dehydrogenase, mitochondrialtarget
Valproic acidSuccinate-semialdehyde dehydrogenase, mitochondrialtarget
Valproic acidSodium channel proteintarget
Valproic acidHistone deacetylase 2target
Valproic acidPeroxisome proliferator-activated receptor alphatarget
Valproic acidPeroxisome proliferator-activated receptor deltatarget
Valproic acidPeroxisome proliferator-activated receptor gammatarget
Valproic acidSerum albumincarrier
Valproic acidUDP-glucuronosyltransferase 1-1enzyme
Valproic acidSolute carrier organic anion transporter family member 2B1transporter
RidogrelThromboxane-A synthasetarget
RidogrelThromboxane A2 receptortarget
GemfibrozilPeroxisome proliferator-activated receptor alphatarget
GemfibrozilCytochrome P450 2C9enzyme
GemfibrozilCytochrome P450 2C8enzyme
GemfibrozilCytochrome P450 1A2enzyme
GemfibrozilCytochrome P450 2C19enzyme
GemfibrozilUDP-glucuronosyltransferase 1-1enzyme
GemfibrozilCytochrome P450 3A4enzyme
GemfibrozilUDP-glucuronosyltransferase 1-3enzyme
GemfibrozilSolute carrier organic anion transporter family member 1B1target
GemfibrozilUDP-glucuronosyltransferase 2B7enzyme
GemfibrozilUDP-glucuronosyltransferase 1-9enzyme
GemfibrozilUDP-glucuronosyltransferase 2B4enzyme
GemfibrozilUDP-glucuronosyltransferase 2B17enzyme
GemfibrozilSerum albumincarrier
GemfibrozilSolute carrier family 22 member 8target
GemfibrozilSolute carrier organic anion transporter family member 2B1target
GemfibrozilSolute carrier organic anion transporter family member 1B3target
Isovaleric AcidAspartate aminotransferasetarget
Isovaleric AcidPseudomonalisintarget
Isovaleric Acid2-hydroxy-6-oxo-7-methylocta-2,4-dienoate hydrolasetarget
5-phenylpentanoic acidAromatic-amino-acid aminotransferasetarget
alpha-KetoisovalerateBranched-chain-amino-acid aminotransferase, mitochondrialtarget
alpha-Ketoisovalerate3-methyl-2-oxobutanoate hydroxymethyltransferasetarget
alpha-KetoisovalerateDeacetoxycephalosporin C synthasetarget
alpha-Ketoisovalerate2-isopropylmalate synthasetarget
alpha-KetoisovalerateMonocarboxylate transporter 2transporter
alpha-KetoisovalerateMonocarboxylate transporter 1transporter
alpha-KetoisovalerateMonocarboxylate transporter 4transporter
ValpromideLimonene-1,2-epoxide hydrolasetarget
DexloxiglumideCholecystokinin receptor type Atarget
DexloxiglumideCytochrome P450 3A4enzyme
DexloxiglumideCytochrome P450 2C9enzyme
DexloxiglumideCytochrome P450 3A5enzyme
DexloxiglumideCytochrome P450 2B6enzyme
DexloxiglumideCytochrome P450 2E1enzyme
EmricasanCaspase-1target
EmricasanCaspase-3target
EmricasanCaspase-7target
FiboflaponArachidonate 5-lipoxygenase-activating proteintarget
MonensinP-glycoprotein 1transporter
KH064Phospholipase A2, membrane associatedtarget