Hydroxyprogesterones

Name
Hydroxyprogesterones
Accession Number
DBCAT000991
Description

Metabolites or derivatives of PROGESTERONE with hydroxyl group substitution at various sites.

Drugs
DrugDrug Description
Medroxyprogesterone acetateA progestin used as a contraceptive and in the treatment of secondary amenorrhea, abnormal uterine bleeding, pain from endometriosis, endometrial and renal carcinomas, paraphilia in males, and GnRH-dependent precocious puberty.
HydroxyprogesteroneNot Annotated
Hydroxyprogesterone caproateA synthetic progestin used for the prevention of spontaneous preterm births in singleton pregnancies in women who have previously had a spontaneous preterm birth.
Drugs & Drug Targets
DrugTargetType
Medroxyprogesterone acetateProgesterone receptortarget
Medroxyprogesterone acetateEstrogen receptor alphatarget
Medroxyprogesterone acetateCytochrome P450 3A4enzyme
Medroxyprogesterone acetateCytochrome P450 2C8enzyme
Medroxyprogesterone acetate3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2enzyme
Medroxyprogesterone acetateCytochrome P450 2C9enzyme
Medroxyprogesterone acetateCytochrome P450 3A1enzyme
Medroxyprogesterone acetateSerum albumincarrier
Medroxyprogesterone acetateP-glycoprotein 1target
Medroxyprogesterone acetateGABA(A) Receptortarget
Medroxyprogesterone acetateP-glycoprotein 1transporter
HydroxyprogesteroneCytochrome P450 3A4enzyme
Hydroxyprogesterone caproateProgesterone receptortarget
Hydroxyprogesterone caproateCytochrome P450 3A4enzyme
Hydroxyprogesterone caproateCytochrome P450 3A5enzyme
Hydroxyprogesterone caproateCytochrome P450 2C19enzyme