Aporphines

Name

Aporphines

Accession Number

DBCAT001090

Description

Dibenzoquinolines derived in plants from (S)-reticuline (BENZYLISOQUINOLINES).

Drugs

Drug	Drug Description
Apomorphine	A morphine derivative D2 dopamine agonist used to treat hypomobile "off" episodes of advanced Parkinson's disease.

Drugs & Drug Targets

Drug	Target	Type
Apomorphine	Dopamine D2 receptor	target
Apomorphine	Dopamine D1 receptor	target
Apomorphine	Dopamine D4 receptor	target
Apomorphine	Dopamine D3 receptor	target
Apomorphine	Dopamine D5 receptor	target
Apomorphine	Alpha-2C adrenergic receptor	target
Apomorphine	Alpha-2B adrenergic receptor	target
Apomorphine	5-hydroxytryptamine receptor 2C	target
Apomorphine	5-hydroxytryptamine receptor 1A	target
Apomorphine	5-hydroxytryptamine receptor 2A	target
Apomorphine	5-hydroxytryptamine receptor 2B	target
Apomorphine	Alpha-2A adrenergic receptor	target
Apomorphine	5-hydroxytryptamine receptor 1D	target
Apomorphine	5-hydroxytryptamine receptor 1B	target
Apomorphine	Catechol O-methyltransferase	enzyme
Apomorphine	Sulfotransferase 1A1	enzyme
Apomorphine	Sulfotransferase 1A2	enzyme
Apomorphine	Sulfotransferase 1A3/1A4	enzyme
Apomorphine	Estrogen sulfotransferase	enzyme
Apomorphine	Sulfotransferase family cytosolic 1B member 1	enzyme
Apomorphine	Cytochrome P450 2B6	enzyme
Apomorphine	Cytochrome P450 2C8	enzyme
Apomorphine	Cytochrome P450 3A4	enzyme
Apomorphine	Cytochrome P450 3A5	enzyme
Apomorphine	UDP-glucuronosyltransferases (UGTs)	enzyme
Apomorphine	Serum albumin	carrier
Apomorphine	Synaptic vesicular amine transporter	transporter