Polymyxins

DBCAT001129Therapeutic categoryJ01XB

Basic lipopeptide antibiotic group obtained from Bacillus polymyxa. They affect the cell membrane by detergent action and may cause neuromuscular and kidney damage. A DrugBank category of 3 drugs. 3 of them are approved.

ATC classification: J — ANTIINFECTIVES FOR SYSTEMIC USE
J01 — ANTIBACTERIALS FOR SYSTEMIC USE
J01X — OTHER ANTIBACTERIALS
J01XB — Polymyxins
Also known as: Polymyxin M · Polymyxin
Drugs: Colistimethate
Colistin
Polymyxin B

What you can answer from here — as of August 24, 2016

3DrugsEach linked to its full drug card

Listed above

2Drug targetsEvery drug–target pair in the class, with bond type

1,446Marketed productsAcross the regions we cover, with dosage forms and routes

19Routes of administrationHow the drugs in this class are given

Which targets do Polymyxins share, and which companies have late-stage candidates in this class?

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