Sleep Initiation and Maintenance Disorders

Name
Sleep Initiation and Maintenance Disorders
Accession Number
DBCAT001294
Description

Not Available

Drugs
DrugDrug Description
ZopicloneA nonbenzodiazepine hypnotic used for the short-term management of insomnia.
LemborexantA dual orexin antagonist indicated for the treatment of sleep-onset and/or sleep maintenance insomnia.
Drugs & Drug Targets
DrugTargetType
ZopicloneTranslocator proteintarget
ZopicloneCytochrome P450 2C8enzyme
ZopicloneCytochrome P450 2C9enzyme
ZopicloneCytochrome P450 3A4enzyme
ZopicloneProstaglandin G/H synthase 1enzyme
ZopicloneGamma-aminobutyric acid receptor subunit alpha-1target
ZopicloneGamma-aminobutyric acid receptor subunit alpha-2target
ZopicloneGamma-aminobutyric acid receptor subunit alpha-3target
ZopicloneGamma-aminobutyric acid receptor subunit alpha-5target
LemborexantOrexin receptor type 1target
LemborexantOrexin receptor type 2target
LemborexantCytochrome P450 3A4enzyme
LemborexantCytochrome P450 3A5enzyme
LemborexantCytochrome P450 3A Subfamilyenzyme
LemborexantCytochrome P450 2B6enzyme
LemborexantP-glycoprotein 1transporter