CCR5 Receptor Antagonists
- Name
- CCR5 Receptor Antagonists
- Accession Number
- DBCAT001623
- Description
Compounds and drugs that inhibit or block the activity of CCR5 RECEPTORS.
- Drugs
Drug Drug Description Maraviroc A CCR5 co-receptor antagonist used with other antiretroviral medications to treat CCR5-tropic HIV-1 infection. Cenicriviroc Cenicriviroc has been used in trials studying the treatment of HIV-infection/AIDS, AIDS Dementia Complex, Nonalcoholic Steatohepatitis, Human Immunodeficiency Virus, and HIV-1-Associated Cognitive Motor Complex. AZD-5672 Azd5672 has been used in trials studying the basic science and treatment of Pharmacokinetics, Renal Impairment, and Rheumatoid Arthritis. PF-232798 PF-232798 is under investigation in clinical trial NCT01140425 (Study To Evaluate The Effect Of A Multiple Oral Dose Of PF-00232798 On QT Intervals In Healthy Subjects). - Drugs & Drug Targets
Drug Target Type Maraviroc C-C chemokine receptor type 5 target Maraviroc Cytochrome P450 3A4 enzyme Cenicriviroc C-C chemokine receptor type 2 target