Nucleic Acid Probes
- Name
- Nucleic Acid Probes
- Accession Number
- DBCAT001716
- Description
Nucleic acid which complements a specific mRNA or DNA molecule, or fragment thereof; used for hybridization studies in order to identify microorganisms and for genetic studies.
- Drugs
Drug Drug Description Mipomersen An oligonucleotide drug used for the treatment of homozygous familial hypercholesterolemia. Bevasiranib Investigated for use/treatment in macular degeneration and diabetic retinopathy. Fomivirsen Indicated for the local treatment of cytomegalovirus (CMV) retinitis in patients with acquired immunodeficiency syndrome (AIDS), when other therapy has been ineffective or is considered unsuitable [FDA Label, L1428]. Patisiran A transthyretin-directed small interfering RNA used to treat polyneuropathy of hereditary transthyretin-mediated amyloidosis. Oblimersen Not Annotated Inotersen An antisense oligonucleotide used to treat polyneuropathy of hereditary transthyretin-mediated amyloidosis. Inclisiran A PCSK9-targeting short interfering RNA (siRNA) that lowers plasma LDL-cholesterol levels. Revusiran Revusiran is under investigation in clinical trial NCT02319005 (ENDEAVOUR: Phase 3 Multicenter Study of Revusiran (ALN-TTRSC) in Patients With Transthyretin (TTR) Mediated Familial Amyloidotic Cardiomyopathy (FAC)). Golodirsen A drug used to treat certain mutations that cause Duchenne muscular dystrophy (DMD). - Drugs & Drug Targets