Exopeptidases

Name
Exopeptidases
Accession Number
DBCAT001912
Description

A sub-class of PEPTIDE HYDROLASES that act only near the ends of polypeptide chains.

Drugs
DrugDrug Description
GlucarpidaseA carboxypeptidase enzyme used to treat toxic plasma methotrexate concentrations by providing an alternate elimination pathway for methotrexate in patients who have impaired renal function.
Cerliponase alfaAn enzyme replacement therapy used to treat neuronal ceroid lipofuscinosis type 2 (CLN2) disease, also known as tripeptidyl peptidase 1 (TPP1) deficiency.
Drugs & Drug Targets
DrugTargetType
GlucarpidaseMethotrexatetarget
Cerliponase alfaCation-independent mannose-6-phosphate receptortarget