Exopeptidases

Name
Exopeptidases
Accession Number
DBCAT001912
Description

A sub-class of PEPTIDE HYDROLASES that act only near the ends of polypeptide chains.

Drugs
DrugDrug Description
GlucarpidaseA carboxypeptidase enzyme used to reduce plasma concentrations of methotrexate in patients with impaired renal function.
Cerliponase alfaAn enzyme replacement therapy used to treat neuronal ceroid lipofuscinosis type 2 (CLN2) disease, also known as tripeptidyl peptidase 1 (TPP1) deficiency.
Alunacedase alfaAlunacedase alfa is a recombinant and soluble glycosylated form of human ACE2. This recombinant version of the enzyme has antihypertensive and potential antineoplastic activities.
Drugs & Drug Targets
DrugTargetType
Cerliponase alfaCation-independent mannose-6-phosphate receptortarget