- Accession Number
A sub-class of PEPTIDE HYDROLASES that act only near the ends of polypeptide chains.
Drug Drug Description Glucarpidase A carboxypeptidase enzyme used to treat toxic plasma methotrexate concentrations by providing an alternate elimination pathway for methotrexate in patients who have impaired renal function. Cerliponase alfa An enzyme replacement therapy used to treat neuronal ceroid lipofuscinosis type 2 (CLN2) disease, also known as tripeptidyl peptidase 1 (TPP1) deficiency.
- Drugs & Drug Targets
Drug Target Type Glucarpidase Methotrexate target Cerliponase alfa Cation-independent mannose-6-phosphate receptor target