Immunoglobulin Fab Fragments

DBCAT001914Pharmacologic class

Univalent antigen-binding fragments composed of one entire IMMUNOGLOBULIN LIGHT CHAIN and the amino terminal end of one of the IMMUNOGLOBULIN HEAVY CHAINS from the hinge region, linked to each other by disulfide bonds. Fab contains... A DrugBank category of 8 drugs. 3 of them are approved.

Also known as: Fab Fragment Immunoglobulins · Fab Fragment, Immunoglobulin · Fab Fragments · Fab Fragments, Immunoglobulin · Fab Immunoglobulin Fragments
Drugs: Abciximab
Caplacizumab
Certolizumab pegol
Gancotamab
Gontivimab
Pexelizumab
Sonelokimab
Vobarilizumab

What you can answer from here — as of August 24, 2016

8DrugsEach linked to its full drug card

Listed above

14Drug targetsEvery drug–target pair in the class, with bond type

98Marketed productsAcross the regions we cover, with dosage forms and routes

3Routes of administrationHow the drugs in this class are given

Which targets do Immunoglobulin Fab Fragments share, and which companies have late-stage candidates in this class?

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