Non-Nucleoside Reverse Transcriptase Inhibitors

Name
Non-Nucleoside Reverse Transcriptase Inhibitors
Accession Number
DBCAT002245
Description

Not Available

ATC Classification
Drugs
DrugDrug Description
DelavirdineA non-nucleoside reverse transcriptase inhibitor used to treat HIV infection.
EtravirineA non-nucleoside reverse transcriptase inhibitor (NNRTI) used in the treatment of HIV-1 infections in combination with other antiretroviral agents.
NevirapineA non-nucleoside reverse transcriptase inhibitor used as part of a management regimen for HIV-1 virus infection.
EfavirenzA non-nucleoside reverse transcriptase inhibitor used to treat HIV infection or prevent the spread of HIV.
RilpivirineA non-nucleoside reverse transcriptase inhibitor (NNRTI) used in combination with other antiretrovirals to specifically treat human immunodeficiency virus type 1 (HIV-1).
DoravirineA non-nucleoside reverse transcriptase inhibitor used in combination with other antiretrovirals to treat HIV-1 infections.
OpaviralineNot Available
CapravirineInvestigated for use/treatment in acquired immune deficiency syndrome (AIDS) and aids-related infections and HIV infection.
Drugs & Drug Targets
DrugTargetType
DelavirdineCytochrome P450 3A4enzyme
DelavirdineCytochrome P450 2C9enzyme
DelavirdineCytochrome P450 2D6enzyme
DelavirdineCytochrome P450 3A5enzyme
DelavirdineCytochrome P450 3A7enzyme
DelavirdineCytochrome P450 2C19enzyme
DelavirdineReverse transcriptase/RNaseHtarget
EtravirineCytochrome P450 2C19enzyme
EtravirineCytochrome P450 2C9enzyme
EtravirineCytochrome P450 3A4enzyme
EtravirineGag-Pol polyproteintarget
EtravirineGag-Pol polyproteintarget
EtravirineP-glycoprotein 1transporter
EtravirineMultidrug resistance protein 3transporter
NevirapineCytochrome P450 3A4enzyme
NevirapineCytochrome P450 2B6enzyme
NevirapineCytochrome P450 3A5enzyme
NevirapineCytochrome P450 2C9enzyme
NevirapineCytochrome P450 2A6enzyme
NevirapineCytochrome P450 2D6enzyme
NevirapineReverse transcriptase/RNaseHtarget
NevirapineSerum albumincarrier
NevirapineCytochrome P450 1A2enzyme
NevirapineSolute carrier family 22 member 1transporter
NevirapineCytochrome P450 3A7enzyme
EfavirenzCytochrome P450 2B6enzyme
EfavirenzCytochrome P450 3A4enzyme
EfavirenzCytochrome P450 2C19enzyme
EfavirenzCytochrome P450 2C9enzyme
EfavirenzCytochrome P450 1A2enzyme
EfavirenzCytochrome P450 2D6enzyme
EfavirenzReverse transcriptase/RNaseHtarget
EfavirenzCytochrome P450 2C8enzyme
EfavirenzSerum albumincarrier
EfavirenzCytochrome P450 3A5enzyme
EfavirenzCytochrome P450 3A7enzyme
EfavirenzUDP-glucuronosyltransferase 1-1enzyme
EfavirenzBile salt export pumptransporter
EfavirenzSolute carrier family 22 member 1transporter
RilpivirineCytochrome P450 3A4enzyme
RilpivirineReverse transcriptase/RNaseHtarget
RilpivirineNuclear receptor subfamily 1 group I member 2target
RilpivirineCytochrome P450 2C19enzyme
RilpivirineCytochrome P450 2B6enzyme
RilpivirineP-glycoprotein 1transporter
RilpivirineATP-binding cassette sub-family G member 2transporter
RilpivirineSolute carrier organic anion transporter family member 1B1transporter
RilpivirineSolute carrier organic anion transporter family member 1B3transporter
RilpivirineSerum albumincarrier
RilpivirineCytochrome P450 2D6enzyme
RilpivirineCytochrome P450 2C9enzyme
RilpivirineCytochrome P450 2C8enzyme
RilpivirineCytochrome P450 2E1enzyme
DoravirineCytochrome P450 3A4enzyme
DoravirineCytochrome P450 3A5enzyme
DoravirineReverse transcriptase/RNaseHtarget
OpaviralineGag-Pol polyproteintarget
CapravirineCytochrome P450 3A4enzyme
CapravirineGag-Pol polyproteintarget
CapravirineCytochrome P450 2C8enzyme
CapravirineCytochrome P450 2C9enzyme
CapravirineCytochrome P450 2C19enzyme