Fatty Acid Derivatives

Name
Fatty Acid Derivatives
Accession Number
DBCAT002301
Description

Not Available

ATC Classification
Drugs
DrugDrug Description
Valproic acidAn anticonvulsant used to control complex partial seizures and both simple and complex absence seizures.
ProgabideIndicated for the treatment of epilepsy.
TiagabineAn antiepileptic used to treat partial seizures.
VigabatrinAn irreversible GABA transaminase inhibitor used as an adjunct therapy to treat refractory complex partial seizures in patients ≥2 years unresponsive to alternatives. May also be used as monotherapy to treat infantile spasms in infants 1 month to 2 years.
ValpromideA valproic acid derivative used to treat epilepsy and as adjunct therapy for psychomotor agitation, depression, and manic episodes of bipolar disorder.
Drugs & Drug Targets
DrugTargetType
Valproic acidHistone deacetylase 9target
Valproic acidShort/branched chain specific acyl-CoA dehydrogenase, mitochondrialtarget
Valproic acidCytochrome P450 2A6enzyme
Valproic acidCytochrome P450 2B6enzyme
Valproic acidCytochrome P450 2C9enzyme
Valproic acidOrganic cation/carnitine transporter 2transporter
Valproic acidSolute carrier family 22 member 6transporter
Valproic acidOrganic anion transporter 3transporter
Valproic acidMonocarboxylate transporter 1transporter
Valproic acidSolute carrier family 22 member 7transporter
Valproic acidCytochrome P450 3A5enzyme
Valproic acidUDP-glucuronosyltransferase 1A9enzyme
Valproic acidProstaglandin G/H synthase 1enzyme
Valproic acidCytochrome P450 1A2enzyme
Valproic acidCytochrome P450 2C19enzyme
Valproic acidCytochrome P450 3A4enzyme
Valproic acidUDP-glucuronosyltransferase 1A4enzyme
Valproic acidUDP-glucuronosyltransferase 1A8enzyme
Valproic acidUDP-glucuronosyltransferase 1A10enzyme
Valproic acidUDP-glucuronosyltransferase 1-6enzyme
Valproic acidUDP-glucuronosyltransferase 1A3enzyme
Valproic acidUDP-glucuronosyltransferase 2B7enzyme
Valproic acidUDP-glucuronosyltransferase 2B15enzyme
Valproic acid2-oxoglutarate dehydrogenase complex component E1target
Valproic acidSuccinate-semialdehyde dehydrogenase, mitochondrialtarget
Valproic acidSodium channel proteintarget
Valproic acidHistone deacetylase 2target
Valproic acidPeroxisome proliferator-activated receptor alphatarget
Valproic acidPeroxisome proliferator-activated receptor deltatarget
Valproic acidPeroxisome proliferator-activated receptor gammatarget
Valproic acidAlbumincarrier
Valproic acidUDP-glucuronosyltransferase 1A1enzyme
Valproic acidSolute carrier organic anion transporter family member 2B1transporter
Valproic acidHistone deacetylasetarget
Valproic acidCyclin-dependent kinase inhibitor 1target
Valproic acidHepatocyte growth factortarget
Valproic acidOrnithine decarboxylasetarget
Valproic acidProgrammed cell death 1 ligand 1target
Valproic acid4-aminobutyrate aminotransferase, mitochondrialtarget
Valproic acidGlycogen synthase kinase-3 alphatarget
ProgabideGamma-aminobutyric acid receptor subunit alpha-1target
ProgabideGamma-aminobutyric acid type B receptor subunit 1target
ProgabideGamma-aminobutyric acid type B receptor subunit 2target
TiagabineSodium- and chloride-dependent GABA transporter 1target
TiagabineCytochrome P450 3A4enzyme
TiagabineUDP-glucuronosyltransferase 1A1enzyme
Vigabatrin4-aminobutyrate aminotransferase, mitochondrialtarget
VigabatrinProton-coupled amino acid transporter 1transporter
VigabatrinCytochrome P450 2C9enzyme
ValpromideLimonene-1,2-epoxide hydrolasetarget